Phosphorylated, ATP-bound, inhibitor 172-bound E1371Q human cystic fibrosis transmembrane conductance regulator
收藏Protein Data Bank Japan2025-05-28 更新2026-04-25 收录
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Phosphorylated, ATP-bound, inhibitor 172-bound E1371Q human cystic fibrosis transmembrane conductance regulator Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 4-[(Z)-{(3M)-4-oxo-2-sulfanylidene-3-[3-(trifluoromethyl)phenyl]-1,3-thiazolidin-5-ylidene}methyl]benzoic acid, ADENOSINE-5'-TRIPHOSPHATE, ... Authors: Gao, X, Hwang, T. Deposit date: 2023-12-04 Release date: 2024-07-17 Last modified: 2025-05-28 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Allosteric inhibition of CFTR gating by CFTRinh-172 binding in the pore. Nat Commun, 15, 2024
创建时间：
2023-12-04
