Association between SNPs and the longitudinal changes from normal to overweight/obesity (BMI ≥25) in the adult (HUNT2 to HUNT3) and the adolescent to adult subsamples (Young-HUNT1 to HUNT3).

In the adult sample, cases (n = 740) were defined with normal weight at HUNT2 and overweight at HUNT3 while controls (n = 1209) were defined as normal weight both at HUNT2 and HUNT3. Overweight at adolescents were assumed according to Cole et al (2001). Cases were defined as normal weight at Young-HUNT1 and overweight (BMI ≥25) at HUNT3 while controls were defined as normal weight both at Young-HUNT1 and HUNT3. All measures were age adjusted and combined samples were additionally sex-adjusted. Empirical P-values were corrected for multiple testing by 1000 permutations.Pa—P-values after multiple testing. Only results with a nominal significant P-value (PbSex interaction PAssociation between SNPs and the longitudinal changes from normal to overweight/obesity (BMI ≥25) in the adult (HUNT2 to HUNT3) and the adolescent to adult subsamples (Young-HUNT1 to HUNT3).