Energy costs (E) of HIV-1 NL4-3 Gag mutants predicted by computational models.
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aE is 2.98 for wild-type NL4-3 p24 and 3.43 for wild-type NL4-3 p17.bE is 3.67 for wild-type NL4-3 p24 and 1.64 for wild-type NL4-3 p17.cE is 4.43 for wild-type NL4-3 p24 and 2.81 for wild-type NL4-3 p17.dThe 198V mutation was not observed within the MSA used to fit the Potts model, precluding the fitted model from assigning an energy to viral strains containing this point mutation.
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2015-12-02



