Closed structure of active SHP2 mutant E76K bound to SHP099 inhibitor
收藏Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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Closed structure of active SHP2 mutant E76K bound to SHP099 inhibitor Descriptor: 6-(4-azanyl-4-methyl-piperidin-1-yl)-3-[2,3-bis(chloranyl)phenyl]pyrazin-2-amine, Tyrosine-protein phosphatase non-receptor type 11 Authors: Padua, R.A.P, Sun, Y, Marko, I, Pitsawong, W, Kern, D. Deposit date: 2018-03-06 Release date: 2018-11-14 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.68 Å) Cite: Mechanism of activating mutations and allosteric drug inhibition of the phosphatase SHP2. Nat Commun, 9, 2018
创建时间：
2018-03-06
