Data for: PhD work from the study of “Polymer self-assemblies: microfluidic production and nucleobase-functionalities”

The data collection encompasses various sources including laboratory notebooks, electronic laboratory notebooks, experiment descriptions and planning, raw and processed data, and Python scripts used for data analysis. All numerical data is provided in .txt or .csv (universal) format wherever possible, except for non-numerical data, such as confocal images, photos and videos.

The enclosed dataset pertains to the characterization of advanced block copolymers and their associated chemical functionalities, synthesized to generate functional self-assemblies:
Nuclear Magnetic Resonance (NMR) Spectroscopy: Utilized for characterizing all synthesized organic compounds, including small organic molecules, monomers, block copolymers, polymers, modified nucleobases, and functionalized polymers. Employed for in operando assessment of the conversion of active esters to amides.
Fourier-Transform Infrared (FTIR) Spectroscopy: Used to analyse the content of active esters and amides within the polymers. Employed for in operando monitoring of the conversion of active esters to amides.
Gel Permeation Chromatography (GPC): Used to determine the molecular weight and dispersity of the synthesized polymers.
Transmission Electron Microscopy (TEM): Utilized to characterise the morphology and size of polymer particles produced via microfluidic mixing.
Dynamic Light Scattering (DLS)/ZetaSizer: Used to measure the size and polydispersity index (PDI) of particles produced through microfluidic mixing.
Small-Angle X-ray Scattering (SAXS): Employed for an in-depth characterization of the particles produced via the microfluidic mixer.
Fluorimeter and UV-Vis Spectroscopy: Used for the quantification of encapsulated and released fluorescent probes.
Confocal Microscopy: Utilized to evaluate micrometre-sized particles/vesicles produced with nucleobase-functionalized polymers. Used to assess the impact of external stimuli (force, temperature, and thymine oligomers) on these vesicles.

This dataset was acquired during research work supported by the Swiss National Science Foundation through the National Centre of Competence in Research Bio-Inspired Materials (NCCR Bio-Inspired Materials, Grant No. 51NF40-182881)