Correction of the DNA Sequence of the regB Gene of Rhodobacter capsulatus with Implications for the Membrane Topology of the Sensor Kinase RegB

We corrected the previously published sequence for the regB gene, which encodes a histidine sensor kinase in Rhodobacter capsulatus. The deduced RegB amino acid sequence has an additional putative transmembrane domain at the N terminus. Analysis of RegB-PhoA and RegB-LacZ fusion proteins supports a topology model for RegB with six membrane-spanning domains.