Enzyme activities (IC50a, μM) of compounds 9–27 against human EGFR and HER2 kinases.
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aConcentration to inhibit by 50% the phosphorylation of a polyglutamic acid/tyrosine random copolymer by EGFR enzyme (prepared from human A431 carcinoma cell vesicles by immunoaffinity chromatography) and HER2 enzyme (prepared from human MCF-7 breast cancer cell vesicles by immunoaffinity chromatography). Mean values in Micromolar, >1 determination.
创建时间：
2015-12-02
