Unc13b
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ENCODES a protein that exhibits calmodulin binding; syntaxin binding; syntaxin-1 binding; INVOLVED IN cellular response to glucose stimulus; dense core granule priming; positive regulation of exocytosis; ASSOCIATED WITH acromesomelic dysplasia, Maroteaux type (ortholog); anauxetic dysplasia (ortholog); autosomal recessive distal hereditary motor neuronopathy 2 (ortholog); FOUND IN cytosol; plasma membrane; synaptic membrane; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; allethrin; ammonium chloride
编码一种表现出钙调蛋白结合、syntaxin结合、syntaxin-1结合的蛋白质;参与细胞对葡萄糖刺激的反应;密集核心颗粒成熟;调节胞吐作用的正向调控;与指端短骨发育不良(同源物)、Maroteaux型(同源物)、生长迟缓性发育不良(同源物)、常染色体隐性远端遗传性运动神经元病2(同源物)相关;存在于细胞质、质膜、突触膜中;与2,3,7,8-四氯二苯并-对-二恶英、除虫菊酯、氯化铵相互作用。
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