Structure and Bioassay of Triterpenoids and Steroids Isolated from Sinocalamus affinis
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Five triterpenoids with a new 25-norfern carbon skeleton (1–5), a lupane triterpenoid (6), and four 20-hydroxyprogesterone acyl esters (7–10), together with 23 known compounds, were isolated from the stem (with skin removed) of Sinocalamus affinis. The absolute configuration of compound 1 was confirmed by single-crystal X-ray crystallographic analysis using anomalous scattering of Cu Kα radiation. Compounds 1–5 exhibited inhibitory activity against protein tyrosine phosphatase 1B.
创建时间:
2016-02-20



