Supporting data: Ageing attenuates exercise-enhanced motor cortical plasticity

In this study, we compared the effects of a single session of cardiorespiratory exercise on motor cortical plasticity in young and older adults. We acquired measures of cortical excitatory and inhibitory activity of the primary motor cortex using transcranial magnetic stimulation (TMS) from 20 young and 20 older healthy adults. Single and paired pulse TMS measures were collected before and after a 20-minute bout of high-intensity interval cycling exercise or an equivalent period of rest, and again after intermittent theta burst stimulation (iTBS).