Loss of the yeast SR protein Npl3 alters gene expression due to transcription readthrough

Yeast Npl3 is a highly abundant RNA binding protein, related to metazoan SR proteins, with reported functions including transcription elongation, splicing and RNA 3’ end processing酵母Npl3是一种丰度极高的RNA结合蛋白（RNA binding protein），与后生动物SR蛋白（SR proteins）具有相关性，其已被报道的功能包括转录延伸（transcription elongation）、剪接（splicing）以及RNA 3'端加工（RNA 3’ end processing）。