RNA-seq transcriptome profiling of motor neurons (MNs) and surrounding white matter glia (WM) microdissected from pre-symptomatic mouse model of spinal muscular atrophy (SMA). Mus musculus

We report tramscriptome perturbations in MNs and WM of SMA mouse, prior to first morphological and biochemical synaptic defects Overall design: Examination of ventral horn MNs and WM isolated from lumbar segment spinal cords from wild type (WT) and SMA mice