LRRK2-Parkinson Disease patients with associated REM sleep behavior disorder.

LEDD: L-Dopa Equivalent daily dose; M+AT: polysomnographic montage quantifying "any" (tonic or phasic) type of EMG activity in the mentalis muscle plus bilateral anterior tibialis phasic EMG activity in REM sleep, using 3-sec mini-epochs (the cut-off for patients with RBD is 46.4%)[38]; Mentalis: EMG activity quantification of "any" (tonic and phasic) type of EMG activity in the mentalis muscle during REM sleep, using 3-sec mini-epochs (the cut-off for patients with RBD is 18.2%.)[38]; MoCA: Montreal Cognitive Assessment; PIGD: postural instability gait difficulty motor subtype; SINBAR: polysomnographyc montage quantifying "any" (tonic or phasic) type of EMG activity in the mentalis muscle and phasic EMG activity in the right and left flexor digitorumsuperficialis muscles during REM sleep, using 3-sec mini-epochs (the cut-off for patients with RBD is 32%)[38]; RBD: REM sleep behaviour disorder; RBDSQ: REM sleep behavior disorder screening questionnaire; UPDRS-III: Unified Parkinson Disease Rating Scale motor exam; V-PSG: video-polysomnography.
LRRK2-Parkinson Disease patients with associated REM sleep behavior disorder.