Tankyrase 1 with Phthalazinone 2
收藏Protein Data Bank Japan2024-03-06 更新2026-03-21 收录
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https://pdbj.org/mine/summary/5ebt
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资源简介：
Tankyrase 1 with Phthalazinone 2 Descriptor: (R,R)-2,3-BUTANEDIOL, 4-[bis(fluoranyl)-[3-[[(6~{S})-6-methyl-3-(trifluoromethyl)-6,8-dihydro-5~{H}-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]carbonyl]phenyl]methyl]-2~{H}-phthalazin-1-one, Tankyrase-1, ... Authors: Kazmirski, S.L, Johannes, J. Deposit date: 2015-10-19 Release date: 2016-03-02 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.24 Å) Cite: Discovery of AZ0108, an orally bioavailable phthalazinone PARP inhibitor that blocks centrosome clustering. Bioorg.Med.Chem.Lett., 25, 2015
创建时间：
2015-10-19
