In vitro and in vivo phenotypes of cut sets.

nd: Not done;#Reaction names is according to MetaCyc database [33].¤LT2 gene numbers.$Growth phenotype is indicated as: +: growth as wild type strain, (+): growth observed but with rates below wild type strain, -: no growth observed.£The media used as input in the model analysis and whether model prediction was considered true depended on the growth phenotype in this medium.¥C.I.: competitive index of 1.00 corresponds to Wild type virulence.#Prediction number in Table S2.*Significantly different from WT strains.**Significantly different from mutated strain without complementation.