Plasma kynurenine mediated pathological communication between gut microbiota and ventricular remodeling in children with pressure overload. Plasma kynurenine mediated pathological communication between gut microbiota and ventricular remodeling in children with pressure overload

Abnormally elevated plasma kynurenine (Kyn) was detected in the patient cohort and single nuclues sequecing revealed its molecular role Overall design: Comparative gene expression profiling analysis of snRNA-seq data for the left ventricle tissue of high Kyn patients and normal Kyn patients