Additional file 16 of Alterations to DNA methylation patterns induced by chemotherapy treatment are associated with negative impacts on the olfactory pathway

Additional file 16. Subset analysis, by time between chemotherapy start date and sample taken, of the association between chemotherapy and DNA methylation in 40,271 promoter regions in 1,808 breast cancer patients with blood specimens (1,066 treated and 742 not treated with chemotherapy) and 337 breast cancer patients with saliva specimens (207 treated and 130 not treated with chemotherapy). Presented here are associations that reached statistical significance at a Bonferroni threshold p-value (p<9.52e-8) within adjustments for batch, immune cell content (LUMP), cell types (only for blood), year of breast cancer diagnosis, and ethnicity. Standard error = stdev.unscaled * s2.post.