PSEN2

ENCODES a protein that exhibits endopeptidase activity (ortholog); INVOLVED IN amyloid-beta metabolic process (ortholog); apoptotic signaling pathway (ortholog); brain morphogenesis (ortholog); PARTICIPATES IN altered Notch signaling pathway involving the macromolecules modifying the main players; Alzheimer's disease pathway; Notch signaling pathway; ASSOCIATED WITH Alzheimer's disease (ortholog); Alzheimer's disease 4 (ortholog); asphyxia neonatorum (ortholog); FOUND IN ciliary basal body (ortholog); cytosol (ortholog); early endosome (ortholog)

编码具有内肽酶活性的蛋白质（同源）；参与淀粉样蛋白-β代谢过程（同源）；凋亡信号通路（同源）；脑形态发生（同源）；参与涉及主要参与者修饰的大分子改变的非典型Notch信号通路；阿尔茨海默病通路；Notch信号通路；与阿尔茨海默病（同源）相关；阿尔茨海默病4（同源）；新生儿窒息（同源）；存在于纤毛基体（同源）；细胞质（同源）；早期内体（同源）