Whole genome sequence data of Mycobacterium tuberculosis and Mycolicibacterium smegmatis mutants of the riboflavin biosynthetic pathway- Part 2
收藏DataCite Commons2026-01-28 更新2026-04-25 收录
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https://datadryad.org/dataset/doi:10.5061/dryad.vq83bk454
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资源简介:
This dataset contains raw whole-genome sequencing data (FASTQ files) for
wild-type and riboflavin biosynthetic gene deletion mutants
of Mycobacterium
tuberculosis and Mycolicibacterium smegmatis. These
strains were generated to investigate the source of metabolic antigens
recognized by mucosal-associated invariant T (MAIT) cells, which detect
intermediates from the riboflavin biosynthetic pathway. To confirm
successful gene deletions and rule out off-target effects, whole-genome
sequencing was performed for each mutant and its corresponding wild-type
strain. This dataset supports the verification of targeted genetic
modifications and enables comparative genomic analyses related to MR1
antigen production in mycobacteria.
提供机构:
Dryad
创建时间:
2025-06-26



