Cryptococcus neoformans protein farnesyltransferase in complex with FPP and inhibitor 2k
收藏Protein Data Bank Japan2023-10-18 更新2026-03-28 收录
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Cryptococcus neoformans protein farnesyltransferase in complex with FPP and inhibitor 2k Descriptor: (2R)-3-(cyclohexylamino)-2-hydroxypropane-1-sulfonic acid, (5S)-4-({1-[(4-bromophenyl)methyl]-1H-imidazol-5-yl}methyl)-5-propyl-1-[3-(trifluoromethoxy)phenyl]piperazin-2-one, 1,2-ETHANEDIOL, ... Authors: Wang, Y, Shi, Y, Beese, L.S. Deposit date: 2021-11-29 Release date: 2022-11-09 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.906 Å) Cite: Structure-Guided Discovery of Potent Antifungals that Prevent Ras Signaling by Inhibiting Protein Farnesyltransferase. J.Med.Chem., 65, 2022
创建时间：
2021-11-29
