Sox2

ENCODES a protein that exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; transcription cis-regulatory region binding; chromatin binding (ortholog); INVOLVED IN adenohypophysis development; positive regulation of cell differentiation; positive regulation of cell-cell adhesion; ASSOCIATED WITH alcohol use disorder; congestive heart failure; Experimental Diabetes Mellitus; FOUND IN nucleus; chromatin (ortholog); cytoplasm (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol 3-benzoate; 2,2',4,4'-Tetrabromodiphenyl ether

编码一种表现出DNA结合转录激活剂活性的蛋白质，RNA聚合酶II特异性；转录顺式调控区结合；染色质结合（同源）；参与腺垂体发育；正调控细胞分化；正调控细胞间粘附；与酒精使用障碍、充血性心力衰竭、实验性糖尿病相关；存在于细胞核、染色质（同源）、细胞质（同源）；与17α-乙炔雌二醇、17β-雌二醇3-苯甲酸酯、2,2',4,4'-四溴二苯醚相互作用。