A Domino Palladium Catalysis: Synthesis of 7-Methyl-5H-dibenzo[a,c][7] annulen-5-ones
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http://www.thieme-connect.com/DOI/DOI?10.1055/s-0033-1338438
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资源简介:
A domino Pd-catalyzed reaction of 1-(2-bromophenyl)ethanones for the synthesis of novel 7-methyl-5H-dibenzo[a,c][7]annulen-5-ones, a carbon core structure present in colchicinoid natural products, is presented. The reaction is proposed to proceed via intermolecular homobiaryl coupling and intramolecular aldol condensation.
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© Georg Thieme Verlag
创建时间:
2013-08-01



