Mouse challenge study design.
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On the indicated days, 11 groups of mice (n = 16 per group) were vaccinated with rHA and challenged with infectious PR8 virus.*All mice were bled for sera on the indicated days and all survivors were bled at study conclusion (Blood).**Some mice (n = 1–3) were sacrificed for bronchoalveolar lavage (BAL). Phosphate buffer saline (PBS), AddaVax™ adjuvant (Adj).
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2015-12-02



