Table 2 in Monoterpene indole alkaloids from Vinca minor L. (Apocynaceae): Identification of new structural scaffold for treatment of Alzheimer's disease

Table 2 Comparison of experimental NMR data of this work with those presented by Farahanikia et al. (2011) for the very same structure of vincaminoreine 2. The specific optical rotation was consistent with the published one by Farahanikia et al. (2011) and Mokrý et al. (1964). 1 H and 13 C NMR chemical shifts are assigned to the related position in ppm with coupling constants for 1 H NMR (in parenthesis, reported in Hz)..
PositionExperimental vincaminoreine 2published vincaminoreine 2 (Farahanikia et al., 2011)500 MHz, CDCl3125 MHz, CDCl3500 MHz, CDCl3125 MHz, CDCl32139.3139.333.90, dd (4.8, 2.9)38.11.96–1.93, m33.842.46, dd (13.7, 2.9)33.92.95–2.93, m22.51.97, d (13.7)538.124.861.43–1.36, m34.21.35–1.30, m31.01.24–1.12, m1.20–1.18, m71.54–1.44, m22.51.54–1.47, m22.31.35–1.24, m1.29–1.25, m82.38–2.32, m55.32.51–2.49, m53.32.32–2.20, m2.27–2.24, m102.55–2.50, m53.32.33–2.29, m55.32.32–2.20, m2.29–2.27, m113.00–2.89, m22.31.41–1.36, m34.21.18–1.16, m12110.0110.013127.1127.1147.50, dd (7.8, 1.0)118.07.50, d (7.1)118.0157.18, td (7.8, 1.0)118.57.17, t (7.0)120.6167.09, td (7.8, 1.0)120.67.07, t (7.0)118.5177.26, dd (7.8, 1.0)108.67.24, overlap108.618136.8136.7193.16, d (12.5)57.93.16, d (15.0)57.91.61, d (12.5)1.61, d (15.0)201.35–1.24, m31.01.25–1.20, m14.21.24–1.12, m210.95, t (7.5)7.40.93, t (7.2)7.4C= O175.2175.23-COOCH33.71, s52.53.70, s52.5NCH33.54, s30.23.52, s30.2[a]D+ 27.6 (c 0.18, CHCl3)+ 26.5 (CHCl3)(Farahanikia et al., 2011; Mokrý et al., 1964)