We performed CRISPR screens on both a sub-library and a genome-wide scale in human intestinal organoids to discover cancer driver genes. We investigated the Wnt and the TGFB pathway and used both WT,

NIAID Data Ecosystem30

Additional file 1: of LNDriver: identifying driver genes by integrating mutation and expression data based on gene-gene interaction network

癌症驱动基因

头颈鳞状细胞癌机制

The candidate drivers with p-values less than 0.05 in HNSC. (XLS 20 kb)

Figshare2016-12-24 更新60

Total number of non-silent mutations in the top predicted genes by different methods trained on the TUSON database.

癌症驱动基因

基因突变分析

Total number of non-silent mutations in the top predicted genes by different methods trained on the TUSON database.

NIAID Data Ecosystem40

COSMIC non-coding variants mapped to z-score ≤ -1 cancer driver sequences.

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