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Crystal Structure of the full-length wild-type PKA RIa Holoenzyme

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Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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Crystal Structure of the full-length wild-type PKA RIa Holoenzyme Descriptor: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, cAMP-dependent protein kinase catalytic subunit alpha, ... Authors: Lu, T, Wu, J, Taylor, S.S. Deposit date: 2019-01-15 Release date: 2019-07-24 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3.55 Å) Cite: Two PKA RI alpha holoenzyme states define ATP as an isoform-specific orthosteric inhibitor that competes with the allosteric activator, cAMP. Proc.Natl.Acad.Sci.USA, 116, 2019
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2019-01-15
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