Structure of BACE Bound to 2-imino-3-methyl-5,5-diphenylimidazolidin-4-one
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Structure of BACE Bound to 2-imino-3-methyl-5,5-diphenylimidazolidin-4-one Descriptor: (2E)-2-imino-3-methyl-5,5-diphenylimidazolidin-4-one, Beta-secretase 1, L(+)-TARTARIC ACID Authors: Strickland, C, Cumming, J. Deposit date: 2012-02-02 Release date: 2012-03-21 Last modified: 2024-11-06 Method: X-RAY DIFFRACTION (1.8 Å) Cite: Structure based design of iminohydantoin BACE1 inhibitors: Identification of an orally available, centrally active BACE1 inhibitor. Bioorg.Med.Chem.Lett., 22, 2012
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2012-02-02
