Regulation of cell growth rate is essential for maintaining cellular homeostasis and survival in diverse conditions. Changes in cell growth rate are accompanied by changes in total cellular RNA conten
Examine the chormatin localization of DINO in DNA damaged human U2OS cells using DINO ChIRP-seq. Overall design: DINO is a DNA damage induced long noncoding RNA required for the transactivation of sev
BackgroundRho GTPases control many cellular processes, including cell survival, gene expression and migration. Rho proteins reside mainly in the cytosol and are targeted to the plasma membrane (PM) up
The DNA damage checkpoint, when activated in response to genotoxic damage during S phase, arrests cells in G2 phase of the cell cycle. ATM, ATR, Chk1 and Chk2 kinases are the main effectors of this ch