FREP3 is a determinant of resistance to schistosome infection in snails (part 2)

Transcriptional profile of BS-90 snails injected with a cocktail of four FREP3 specific 27-mer DSiRNA oligos and two hours later exposed to S. mansoni miricidia. Compared to BS-90 snails injected with a cocktail of three GFP specific DSiRNA oligos and two hours later exposed to S. mansoni miricidia. Experiments were done over the course of 49 days. Snails were collected (10each) at 2 and 4 dpe to S. mansoni for comparison. Each replicate is comprised of 1 individual snail from the specified treatment group. Ten replicates of each treatment were analyzed on the Snail oligo array.