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Asymmetric Hydroformylation of Vinyl Acetate: Application in the Synthesis of Optically Active Isoxazolines and Imidazoles

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NIAID Data Ecosystem2026-03-06 收录
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https://figshare.com/articles/dataset/Asymmetric_Hydroformylation_of_Vinyl_Acetate_Application_in_the_Synthesis_of_Optically_Active_Isoxazolines_and_Imidazoles/2998585
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资源简介:
(R)- and (S)-2-(Acetyloxy)-propanal were prepared [93.8% ee, 102 b/l for (R), 96.9% ee, 149 b/l for (S)] via asymmetric hydroformylation of vinyl acetate on a 150−180 g scale and were used as the starting materials in the synthesis of chiral isoxazoline and imidazole derivatives which proceeded without racemization of the chiral center.
创建时间:
2016-02-29
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