Crystal Structure of an MDM2/Nutlin-3a complex
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Crystal Structure of an MDM2/Nutlin-3a complex Descriptor: 4-({(4S,5R)-4,5-bis(4-chlorophenyl)-2-[4-methoxy-2-(propan-2-yloxy)phenyl]-4,5-dihydro-1H-imidazol-1-yl}carbonyl)piperazin-2-one, E3 ubiquitin-protein ligase Mdm2, SULFATE ION Authors: Noble, M.E.M, Anil, B, Riedinger, C, Endicott, J.A. Deposit date: 2012-10-07 Release date: 2013-07-31 Last modified: 2024-02-28 Method: X-RAY DIFFRACTION (1.6 Å) Cite: The structure of an MDM2-Nutlin-3a complex solved by the use of a validated MDM2 surface-entropy reduction mutant. Acta Crystallogr.,Sect.D, 69, 2013
创建时间:
2012-10-07



