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Chiral Brønsted Acid Catalyzed Enantioselective Addition of α-Isocyanoacetamides to Aldehydes

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NIAID Data Ecosystem2026-03-06 收录
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https://figshare.com/articles/dataset/Chiral_Br_nsted_Acid_Catalyzed_Enantioselective_Addition_of_Isocyanoacetamides_to_Aldehydes/2768191
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资源简介:
A clean and highly efficient enantioselective addition of α-isocyanoacetamides to aliphatic aldehydes catalyzed by chiral phosphoric acid in the presence of MS 5 Å in toluene at −40 °C was developed. Excellent yields (85−98%) and good to excellent enantioselectivities (up to >99% ee) were achieved.
创建时间:
2016-02-24
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