New ruthenium(II) arene derivatives (arene = p-cymene, benzene, hexamethylbenzene) containing β-ketoamine ligands L′ (HL′ in general; in detail, HLph,ph = (4Z)-3-methyl-4-((phenylamino)(phenyl)meth

NIAID Data Ecosystem50

Cancer stem cells, not bulk tumor cells, determine mechanisms of resistance to SMO inhibitors, RNA-seq

癌细胞耐药性

髓母细胞瘤药物响应

RNAseq samples from fSmoM2;hGFAPcre spontaneous medulloblastoma and treated with vehicle or LDE225. RNAseq samples from Ptch;p53 SI-CSC or SD-CSV tumors treated with vehicle or LDE225

NIAID Data Ecosystem20

BRAFi and/or MEKi resistance in A375 cell line

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