Monika Zmojdzian, Jean Philippe Da Ponte, Krzysztof Jagla (2011) CIL:25536, Drosophila melanogaster, cardioblast (sensu Arthropoda), pericardial cell, cardiac outflow muscle, heart-anchoring cells, cephalic vascular rudiment cells. CIL. Dataset

The final morphogenesis of the cardiac outflow tract (OFT) depends on coordinated cell-cell interactions among the heart tip, migrating heart-anchoring cells (HANCs) and the dorsally growing cardiac outflow muscles (COMs). This is a three-dimensional reconstruction of the cardiac outflow tract (horizontal rotation) from stage-16 wild-type embryos stained for Ladybird early (Lbe; blue), Msp300 (green), and Tinman (Tin; red). HANC cells (in blue) overlap dorsally the most anterior aorta. The COM muscles (in green) are attached on both sides to the most anterior Lbe-expressing cardioblasts (at this stage Lbe expression in the cardioblasts and pericardial cells is very week, and rendering Lbe signal visible resulted in an increased background). Note that ventrally to the tip of aorta are located cephalic vascular rudiment cells (cvr), which are Tin-positive, Msp300-negative. Movie is SI Movie 1A in Proc Natl Acad Sci USA (2008) 105: 2475-2480. Movies from this publication include CIL# 25536, 25537, 25538, 25539, 25540, 25541.

心输出道（OFT）的最终形态发生依赖于心脏尖端、迁移的心锚定细胞（HANCs）与背侧生长的心输出肌肉（COMs）之间的协调的细胞间相互作用。此为对16期野生型胚胎进行Ladybird早期（Lbe；蓝色）、Msp300（绿色）和Tinman（Tin；红色）染色的心输出道（水平旋转）的三维重建。HANC细胞（蓝色）在背侧与最前端的主动脉重叠。COM肌肉（绿色）两侧附着于最前端的Lbe表达的心肌原细胞（在此阶段，心肌原细胞和心包细胞的Lbe表达非常微弱，导致背景信号增强）。请注意，主动脉尖端腹侧位于头侧血管原基细胞（cvr），这些细胞为Tin阳性，Msp300阴性。此电影为《Proc Natl Acad Sci USA》（2008）第105卷第2475-2480页中的SI Movie 1A。该出版物中的电影包括CIL# 25536, 25537, 25538, 25539, 25540, 25541。