EC50 Dataset for Selection of HIV-1 for Resistance to Fifth Generation Protease Inhibitors Reveals Two Independent Pathways to High-Level Resistance
收藏DataCite Commons2024-02-02 更新2024-07-13 收录
下载链接：
https://cdr.lib.unc.edu/concern/data_sets/pk02cm738
下载链接
链接失效反馈官方服务：
资源简介：
EC50 values were determined for a subset of the selected virus cultures against a panel of protease inhibitors. The highest level of resistance recorded was 100 µM. Using a novel method described in the methods, these values were then pooled using several different parameters as described in the figure legends. EC50 inhibition values are shown in Figure 1 and 5. The Mann-Whitney rank-sum test was used to assess differences in EC50 values. Around 10% of the curves had one point where the value was >125% infectivity of the first point. Anomalous values were excluded from curve fitting. 4 curves did not record data.
提供机构：
The University of North Carolina at Chapel Hill University Libraries
创建时间：
2022-08-13
