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To Identify KRAS Gene and Safe Margin in Association With Outcome in Colorectal Liver Metastases Following Ultrasound-guided Radiofrequency Ablation

NIAID Data Ecosystem2026-03-11 收录

结直肠癌肝转移治疗

KRAS基因功能

数据链接：

https://www.omicsdi.org/dataset/ecrin-mdr-crc/2341429 数据链接链接失效反馈

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资源简介：

To investigate the clinical effect of radiofrequency ablation on colorectal cancer liver metastases with different KRAS gene status

应用场景：

创建时间：

2020-06-15

结直肠癌肝转移治疗

载药微球栓塞术

Purpose: The purpose of this study is: to assess and define the current practice of the delivery of irinotecan loaded drug eluting beads in the treatment of liver metastases from colorectal cancer; to

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RNAseq data comparing iKPC PDAC tumors with KRAS* expression (ON) and KRAS extinction (OFF). RNAseq data comparing iKPC PDAC tumors with KRAS* expression (ON) and KRAS extinction (OFF)

胰腺导管腺癌转录组学

KRAS基因功能

KRAS* is required for PDAC tumor mantainence. To dissect the molecular mechanisms that regulated by KRAS* in PDAC tumors, we conducted RNA-seq analysis of KRAS*-expressing iKPC PDAC tumors and iKPC tu

NIAID Data Ecosystem30

KRAS drives immune evasion in a genetic model of pancreatic cancer [bulk RNA-seq]. KRAS drives immune evasion in a genetic model of pancreatic cancer [bulk RNA-seq]

胰腺癌免疫逃逸

KRAS基因功能

Immune evasion is a hallmark of KRAS-driven cancers, but underlying mechanism and clinical implications remain unclear. Overall design: We used a mouse model of pancreatic carcinogenesis to completely

NIAID Data Ecosystem20

Combination Chemotherapy With or Without Cetuximab Before and After Surgery in Treating Patients With Resectable Liver Metastases Caused By Colorectal Cancer

结直肠癌肝转移治疗

西妥昔单抗辅助化疗

RATIONALE: Drugs used in chemotherapy, such as oxaliplatin, fluorouracil, leucovorin, and capecitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stop

NIAID Data Ecosystem40

Investigation of efficacy and safety of panitumumab in combination with irinotecan/5-fluorouracil/leucovorin (FOLFIRI) in patients with colorectal cancer liver metastasis

结直肠癌肝转移治疗

RAS靶向治疗

Primary objectives: Evaluation of efficacy and safety of perioperative treatment including panitumumab and FOLFIRI as first line therapy for mCRC in subjects with potentially resectable liver metastas

NIAID Data Ecosystem20

To Identify KRAS Gene and Safe Margin in Association With Outcome in Colorectal Liver Metastases Following Ultrasound-guided Radiofrequency Ablation

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