Supplementary Material for: ADRENOCORTICAL CARCINOMA IN PREGNANCY. THE FIRST CASE REPORT IN MEXICO AND REVIEW OF THE LITERATURE.

Adrenocortical carcinoma (ACC) in pregnancy is very rare, with fewer than 20 cases reported in the world literature. The most common form of diagnosis is incidental, occurring during imaging studies. However, in pregnancy, gestational hypertension or preeclampsia is one of the signs frequently associated with functional ACC, particularly with cortisol secretion. Histological diagnosis is the gold standard, and in early stages, surgery is the treatment of choice. The prognosis for ACC is extremely poor, but pregnancy-associated ACC is associated with even shorter survival periods.
We present a case of ACC in pregnancy that presented with preeclampsia and was diagnosed incidentally. This type of presentation represents a clinical challenge and requires multidisciplinary management to improve the patient's survival.