Example ARs and RARs under SMC and ECC with synergy of 0 (ECC0) or 1 (ECC1).
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Note: ARs and RARs are shown as means followed by the 95% prediction intervals. Three probabilities of resistance emergence for drug B are shown here: pB = 0.01, 0.05, and 0.3. Under SMC and ECC1 (ECC with perfect synergy), AR and RAR are insensitive to the value of pB in this range (see Table S2), hence only one set of outcomes is shown.
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2015-12-02



