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Species analysed by CRISPETa and for which off-target databases were compiled.

Figshare2017-03-02 更新2026-04-29 收录

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https://figshare.com/articles/dataset/Species_analysed_by_CRISPETa_and_for_which_off-target_databases_were_compiled_/4717441 数据链接链接失效反馈

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Filtered protospacers are those passing default off-target and efficiency score cutoffs.

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创建时间：

2017-03-02

CRISPR-Cas9基因编辑

蛋白质标记设计

Pythia is a tool for designing CRISPR-Cas9 knock-in strategies for endogenous C-terminal protein tagging, which ranks candidate sgRNA/repair-template combinations based on predicted editing outcomes.

Zenodo2026-04-25 更新30

Decorating chromatin for enhanced genome editing using CRISPR-Cas9

CRISPR-Cas9基因编辑

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To improve the efficiency of homology-directed repair of double-stranded breaks introduced by CRISPR-Cas9, a Cas9-PRDM9 (PR/SET Domain 9) fusion protein was generated and tested in HEK-293T cells. RNA

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Human HFF cells large rearrangements detection after CRISPR-Cas9 nuclease (Fig. 3b)

CRISPR-Cas9基因编辑

遗传效应分析

SORSC1 gene editing by CRISPR-Cas9 nuclease in heterozygous HFF for UROS inactivation. Fluorescent positive cell sorting for UROS and large rearrangements confirmation in chromosome 10q. One condition

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CRISPR-Cas9-based knockout of the prion protein and its effect on the proteome

朊病毒蛋白

CRISPR-Cas9基因编辑

The molecular function of the cellular prion protein (PrPC) and the mechanism by which it may contribute to neurotoxicity in prion diseases and Alzheimer’s disease (AD) are only partially understood.

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DataSheet2_Whole genome sequencing of CCR5 CRISPR-Cas9-edited Mauritian cynomolgus macaque blastomeres reveals large-scale deletions and off-target edits.xlsx

CRISPR-Cas9基因编辑

非人灵长类基因组学

Introduction: Genome editing by CRISPR-Cas9 approaches offers promise for introducing or correcting disease-associated mutations for research and clinical applications. Nonhuman primates are physiolog

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Species analysed by CRISPETa and for which off-target databases were compiled.

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