Chronic exposure to ultraviolet (UV) radiation is known to induce the formation of both cyclobutane pyrimidine dimers (CPDs) and Dewar valence photo-adducts (DVs) in DNA. While CPDs occur at a frequen
As primary p53 antagonists, Mdm2 and the closely related Mdm4 are relevant cancer therapeutic targets. We have previously described a series of cell-permeable stapled peptides that bind to Mdm2 with h
Vitis vinifera (black raisin) is commonly used in traditional medicine for the treatment of various ailments. In the present study, anti-oxidative and anti-cancer efficacy of oleanolic acid from ethyl