Lysosomal multi-omics reveals altered sphingolipid catabolism as driver of lysosomal dysfunction in the aging brain.
收藏Mendeley Data2026-04-09 收录
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Total lipid extracts of mouse brain lysosomes were prepared from 3month, 12month, 18month, and 24month old mice. The lipid composition of these extracts were analyzed by untargeted lipidomics using liquid chromatography coupled to high-resolution tandem mass spectrometry.
