2.26 A resolution structure of MERS 3CL protease in complex with inhibitor 7i
收藏Protein Data Bank Japan2024-10-23 更新2026-03-21 收录
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2.26 A resolution structure of MERS 3CL protease in complex with inhibitor 7i Descriptor: 4,4-difluorocyclohexyl [(2S)-3-cyclohexyl-1-({(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}amino)-1-oxopropan-2-yl]carbamate, Orf1a protein Authors: Lovell, S, Battaile, K.P, Kashipathy, M.M, Rathnayake, A.D, Zheng, J, Kim, Y, Nguyen, H.N, Chang, K.O, Groutas, W.C. Deposit date: 2020-01-09 Release date: 2020-08-12 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.26 Å) Cite: 3C-like protease inhibitors block coronavirus replication in vitro and improve survival in MERS-CoV-infected mice. Sci Transl Med, 12, 2020
创建时间：
2020-01-09
