Interferon Alpha Induces Multiple Cellular Proteins That Coordinately Suppress Hepadnaviral Covalently Closed Circular DNA Transcription
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE134325
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To identify the cellular genes that mediate IFN-α suppression of cccDNA transcription, the total intracellular RNA were extracted from untreated or recombinant chicken IFN-α (rChIFN-α)-treated cells, and mRNA sequencing (mRNA-Seq) assays were performed in triplicate. And we found that treatment of dstet5 cells with 10 ng/ml of rChIFN-α for 6 h altered the expression of more than 100 cellular genes by more than 2 folds. mRNA sequencing (mRNA-Seq) assays were performed in triplicate for untreated or rChIFN-α-treated dstet5 cells
创建时间:
2020-09-18



