Osteoblast signaling

Osteoblasts are specialized, terminally differentiated uninucleated cells responsible for bone formation. Their activity is tightly regulated by external stimuli, originating from e.g. the parathyroid glands, osteocytes, etc. Along with osteoclasts, which are responsible for bone degradation, osteoblasts are key regulators of the shape and volume of bone tissue.

成骨细胞为一种特化的、终末分化的单核细胞，负责骨的形成。其活性受到外部刺激的严格调控，这些刺激源自于甲状旁腺、成骨细胞等。与负责骨降解的破骨细胞共同作用，成骨细胞是调控骨组织形状和体积的关键因素。