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Chromosome 1 tile path array (version 2) analysis of astrocytomas

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE7427
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Copy number assessment of chromosome 1 in astrocytic tumors using a chromosome 1 tile path array. Goal was to determine the patterns of chromosome 1 copy number alterations in astrocytic tumors. Keywords: Comparative Genomic Hybridization Single hybridization per case. 8 diffuse astrocytomas WHO grade II, 16 anaplastic astrocytomas WHO grade III, 72 glioblastomas WHO grade IV were analyzed. Target (tumor) labelled with Cy5 and reference with Cy3. Mixture of 20 normal male or female genomic DNA was used in sex-mismatched hybridization.
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2012-03-17
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