Dnmt3a protects active chromosome domains against cancer-associated hypomethylation
收藏官方服务:
资源简介:
Dnmt3a protects active chromosome domains against cancer-associated hypomethylation
应用场景:
创建时间:
2013-01-22
相关数据集
Global 5mC and 5hmC levels in sixteen pairs of HCC and non-HCC samples and two HCC cell lines investigated by UPLC-MS/MS
We performed UPLC-MS/MS to investigate global 5mC and 5hmC levels in sixteen pairs of HCC and non-HCC samples and two HCC cell lines (97L and LM6 cells). We found that 5mC and 5hmC were frequently dec
Figshare2016-01-19 更新70
Dynamic imbalance between cancer cell subpopulations induced by Transforming Growth Factor Beta (TGF-β) is associated with a DNA methylome switch [methylation]
Distinct subpopulations of neoplastic cells within tumors, including hepatocellular carcinoma (HCC), display pronounced ability to initiate new tumors and induce metastasis. Recent evidence suggests t
NIAID Data Ecosystem40
CENPA as a reader of m6A-modified centromeric RNA to ensure centromere integrity in cancer cells [RIP-Seq]
Maintaining centromere integrity is crucial for genome stability and proper chromosome segregation during mitosis. CENPA, a conserved histone H3 variant, is localized at the centromeres and plays an e
NIAID Data Ecosystem10
Epigenomic study identifies a novel mesenchyme homeobox2-GLI1 transcription axis involved in cancer drug resistance, overall survival and therapy prognosis in lung cancer patients
Several homeobox-related gene (HOX) transcription factors such as mesenchyme HOX-2 (MEOX2) have previously been associated with cancer drug resistance, malignant progression and/or clinical prognostic
DataONE2020-06-24 更新60
DataSheet_1_A Genome-Wide Investigation of Effects of Aberrant DNA Methylation on the Usage of Alternative Promoters in Hepatocellular Carcinoma.zip
BackgroundThe alternative usage of promoters provides a way to regulate gene expression, has a significant influence on the transcriptome, and contributes to the cellular transformation of cancer. How
NIAID Data Ecosystem30



