Anatomical Structures, Cell Types, plus Biomarkers (ASCT+B) table for Lung, v1.5

Anatomical Structures, Cell Types, plus Biomarkers (ASCT+B) tables (https://humanatlas.io/asctb-tables) aim to capture<br>the nested lung structure of anatomical human body parts, the typology of cells, and biomarkers used to identify lung<br>cell types. The tables are authored and reviewed by an international team of experts. The current Lung ASCT+B table is<br>simplified to consider the anatomical and cellular composition of the intra-pulmonary respiratory tract of one lung<br>lobe as representative of the five human lung lobes. The gross anatomy of the lung lobe was highly influenced by<br>Gray's Anatomy The Anatomical Basis of Clinical Practice, the International Federation of Associations of Anatomists:<br>Terminologia Anatomica (TA) and the LungMAP Anatomical Ontology. References are provided for the identification of<br>each cell type in each histologic structure. Cell types were labeled up to the finest level of labeling available,<br>and set to “None” if no cell type label was available at the level under consideration. Uberon and Cell Ontology<br>entries used are as specific to lung and substructures as available. Where cells of similar type are distinguished by<br>occurance in different locations, the closest and highest level of resolution available distinguishing markers is<br>used. The table includes detailed anatomical structures of the branching airway along with associated cell types like<br>multiciliated epithelial cells, secretory cells, and structural cells. This comprehensive mapping supports research<br>into pulmonary biology and related medical<br>conditions. <br><br>**Bibliography:** <br> <br>* Standring, Susan, ed. 2020. Gray’s Anatomy: The Anatomical Basis of Clinical Practice. 42nd ed. London: *Elsevier*.<br>* IFAA and International Federation of Associations of Anatomists. 2025. “*Anatomical Terminology (FIPAT) - IFAA*.” June 15, 2025. https://ifaa.net/committees/anatomical-terminology-fipat/.<br>* Pan, Huaqin, Gail H. Deutsch, Susan E. Wert, Namasivayam Ambalavanan, Charles Ansong, Maryanne E. Ardini-Poleske, Jacqueline Bagwell, et al. 2019. “Comprehensive Anatomic Ontologies for Lung Development: A Comparison of Alveolar Formation and Maturation within Mouse and Human Lung.” *Journal of Biomedical Semantics* 10 (1): 18. https://doi.org/10.1186/s13326-019-0209-1.