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Essential role of the transcription factors E2A and E2-2 in germinal center B cell and plasma cell development

ChEBI2016-06-01 更新2026-07-12 收录

B细胞发育

转录因子功能研究

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-77744 数据链接链接失效反馈

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Essential role of the transcription factors E2A and E2-2 in germinal center B cell and plasma cell development

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创建时间：

2016-06-01

B细胞发育

剪接体功能

The spliceosome is a large ribonucleoprotein complex responsible for pre-mRNA splicing and genome stability maintenance. Disruption of the spliceosome activity may lead to developmental disorders and

NIAID Data Ecosystem60

Early B-Cell Factor (O/E-1) Is a Promoter of Adipogenesis and Involved in Control of Genes Important for Terminal Adipocyte Differentiation

脂肪细胞分化

转录因子功能研究

Olf-1/early B-cell factor (O/E-1) is a transcription factor important for B-lymphocyte and neuronal gene regulation. Here we report that all three known O/E genes (O/E-1, -2, and -3) are expressed in

PubMed Central50

A Congenital Anemia Dissociates the Pleiotropic Functions of Master Transcription Factor GATA1 [G1E_ATACseq]

先天性贫血分子机制

转录因子功能研究

Master regulators, such as the hematopoietic transcription factor GATA1, have numerous roles in lineage commitment and differentiation. While human GATA1 mutations result in several blood diseases, al

NIAID Data Ecosystem40

Polypyrimidine tract binding proteins are essential for B cell development. Polypyrimidine tract binding proteins are essential for B cell development

B细胞发育

转录调控

During B cell development, recombination of immunoglobulin loci is tightly coordinated with the cell cycle to avoid unwanted rearrangements of other genomic locations. Several factors have been identi

NIAID Data Ecosystem50

Gene expression analysis of mouse pancreas carrying Prox1 ectopic acinar expression

胰腺基因表达

转录因子功能研究

RNA sequencing was used to identify gene expression changes in pancreatic acinar cells with ectopic expression of the homeodomain transcription factor Prox1 Overall design: The pancreas P7 control mic

NIAID Data Ecosystem40

Essential role of the transcription factors E2A and E2-2 in germinal center B cell and plasma cell development

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