Thrombin has biphasic effects on cGMP levels in endothelial cells.
收藏Figshare2016-02-29 更新2026-04-29 收录
下载链接：
https://figshare.com/articles/dataset/_Thrombin_has_biphasic_effects_on_cGMP_levels_in_endothelial_cells_/719332
下载链接
链接失效反馈官方服务：
资源简介：
(A) Thrombin (30 nM) acutely increases cGMP content in HUVECs; the effects, however, are transient (white bars: controls; grey bars: with thrombin). (B) cGMP elevation by incubation with the NO donor DETA NONOate (100 µM) is partly blunted by thrombin over 14 to 24 hours. (C) Reduction of cGMP levels in DETA NONOate-stimulated cells is concentration-dependent. (D) Thrombin-induced reduction of cGMP levels over 14 hours in DETA NONOate-stimulated cells is completely abolished by direct thrombin inhibitor melagatran (10 µM). Data shown as mean ± SEM (A, B, C: n = 3; D: n = 4/group). *ppp
创建时间：
2016-02-29
