RAGE and Rap1a in Cardiac Hypertensive Remodeling
收藏DataCite Commons2025-11-19 更新2026-04-25 收录
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https://figshare.com/articles/dataset/RAGE_and_Rap1a_in_Cardiac_Hypertensive_Remodeling/28733219/1
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This study reveals that Rap1a knockout protects against AngII-induced cardiac hypertrophy, while RAGE knockout alters remodeling patterns. Despite genotype, AngII consistently drove structural changes, while diastolic function was genotype-dependent. These findings underscore the therapeutic potential of targeting Rap1a and RAGE signaling pathways to mitigate hypertensive cardiac remodeling.
提供机构:
figshare
创建时间:
2025-11-19



